Tuesday, January 29, 2013

Heart of the Farm ? Women in Agriculture Conference comes to ...

Mark your calendars! A Heart of the Farm ? Women in Agriculture conference will be held at Badgerland Financial, Prairie du Sac, February 15, 2013.

The Heart of the Farm- Women in Agriculture?conference series is a University of Wisconsin-Extension program that is committed to addressing the needs of farm women by providing education on farm business topics, connecting them with agricultural resources and creating support networks.

This conference will provide women with the opportunity to network with other farm women and learn about farm business arrangements; how you, as farm women, can make a difference; and how to balance your life. A special session about cheese will end the day.

The conference begins with registration at 9:15 a.m and will end at 3 p.m. with door prizes. Lunch is being catered by the Blue Spoon Caf?. Topics and presenters include:

  • Badgerland Financial: Paul Dietmann, Assistant Vice President, Emerging Markets Specialist. Paul will review what Badgerland Financial can do for and with you as producers.
  • Farm Bill 2013 ? What May Lie Ahead: Mark Stephenson, UW-Extension dairy policy analyst, Director of Center for Dairy Profitability. Mark will review the farm bill extension, changes in the farm bill environment and potential future policy.
  • Putting a Face and a Place to Food: Lois Federman, WI DATCP.?Local food production is sweeping across the state?s countryside and inside urban areas creating new opportunities forWisconsin farmers. Lois will talk about opportunities that are available for producers to market food products.
  • Keeping Young Hearts Safe on the Farm. Cheryl Skjolaas, UW-Extension outreach specialist, UW Biological Systems Engineering, UW-Madison. The children who may live on your farm or visit need to be aware of the safe and unsafe activities on the farm. Cheryl will discuss the ages and stages of youth development and how to prevent common farm-related injuries for the different age groups; steps to take in an emergency and first aid resources.
  • Cheese tasting from Carr Valley Cheese

Registration is $20 per person. To register, obtain a brochure, or for more information, contact: UW-Extension Sauk County Office, c/o HOF-Sauk, West Square Administration Bldg, 505 Broadway, Baraboo, WI 53913-2404. Registration deadline is February 8, 2013.

Heart of the Farm is supported by theUW-Centerfor Dairy Profitability,UW-Extension Sauk County,WisconsinMilk Marketing Board, Farm Service Agency, and a USDA Risk Management Agency grant.

For more information on the conference Heart of the Farm Program contact: Jenny Vanderlin,?jmvander@wisc.edu, 608.263.7795, website at:?www.uwex.edu/ces/heartofthefarm. Hear what previous Heart of the Farm workshop participants have to say about the program at?www.youtube.com.

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Source: http://wfbf.com/ag-newswire/heart-of-the-farm-women-in-agriculture-conference-comes-to-prairie-du-sac/

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Washington casts wary eye at Muslim Brotherhood

A protester throws a tear gas canister back at riot police during clashes near Tahrir Square, in Cairo, Sunday, Jan. 27, 2013. Clashes continued for the fourth successive day between protesters and police near Tahrir square, birthplace of the 2011 uprising. Police used tear gas, while the protesters pelted them with rocks. (AP Photo/Khalil Hamra)

A protester throws a tear gas canister back at riot police during clashes near Tahrir Square, in Cairo, Sunday, Jan. 27, 2013. Clashes continued for the fourth successive day between protesters and police near Tahrir square, birthplace of the 2011 uprising. Police used tear gas, while the protesters pelted them with rocks. (AP Photo/Khalil Hamra)

People carry the coffin of a man killed during a mass funeral in Port Said, Egypt, Sunday, Jan. 27, 2013. Tens of thousands of mourners poured into the streets of Port Said on Sunday for a funeral for most of the 37 people killed in rioting a day earlier, chanting slogans against Islamist President Mohammed Morsi. (AP Photo)

(AP) ? President Barack Obama begins his second term straining to maintain a good relationship with Egypt, an important U.S. ally whose president is a conservative Islamist walking a fine line between acting as a moderate peace broker and keeping his Muslim Brotherhood party happy with anti-American rhetoric.

The White House last summer had hoped to smooth over some of the traditional tensions between Washington and the Brotherhood, a party rooted in opposition to Israel and the U.S., when Egypt overthrew dictator Hosni Mubarak and picked Mohammed Morsi as its first democratically elected leader.

But a spate of recent steps ? from Brotherhood-led attacks on protesters, to vague protestations of women's freedoms in the nation's new constitution, to revelations of old comments by Morsi referring to Jews as "bloodsuckers" and "pigs" ? have raised alarm among senior U.S. officials and threatens $1 billion in American aid to Egypt.

Though the Brotherhood was founded in Egypt, its influence and affiliates have spread across the Mideast and into North Africa ? where two recent terrorist attacks and a French assault on Islamist militants in Mali have presented Obama with a new front in the battle against extremism for his second term.

The White House has little interest in picking a fight with the Muslim Brotherhood, which has grown in size and stature across the region since the Arab Spring revolts. The Brotherhood and similar Islamist movements are regarded warily by monarchies in Jordan, Kuwait, Saudi Arabia, the United Arab Emirates and Morocco. Its members are part of the opposition coalition seeking to oust Syrian President Bashar Assad. It has small followings in Qatar, Algeria, and a like-minded ? although not officially affiliated ? ally in Tunisia.

When Egyptians elected Morsi, he offered words of moderation, brokered a cease-fire between Israelis and Palestinians in Gaza and bore down on terrorist dens in the Sinai Peninsula.

The Morsi-led government is "a new administration and they're obviously having growing pains," said a senior Obama administration official who agreed to speak on condition of anonymity so he could discuss the diplomatic relationship more candidly.

Since the Tahrir Square revolution two years ago, Washington has tried to help Egypt build a democratic state without appearing to tread on its sovereignty. Morsi won election last June with 51 percent of Egypt's vote.

A new eruption of political violence in Egypt over the weekend left about 50 people dead, deepening the malaise as the Morsi struggles to get a grip on enormous social and economic problems. He has declared a 30-day state of emergency and curfew in the three Suez Canal provinces hit hardest by the violence.

The White House is increasingly concerned about the direction the Brotherhood is taking Egypt: "It's not just about majority rule," the administration official said. "There are democratic principles that we continue to support."

Morsi's anti-Semitic comments, made in separate speeches in 2010 but which surfaced this month on Egyptian TV, also accused Obama of being a liar. They shocked U.S. officials who sprang to condemn them as counter-productive to American-supported peace efforts in the Mideast. But they surprised few people in Egypt, who have heard Brotherhood officials make similar statements for years.

Morsi initially struggled to respond to the U.S. backlash from the comments. His office issued a statement committing to uphold religious freedoms and tolerance, and condemning violence.

"The president strongly believes that we must respect and indeed celebrate our common humanity, and does not accept or condone derogatory statements regarding any religious or ethnic group," the statement said, without addressing the fact that Morsi himself made those comments.

The statement, however, did little to soothe U.S. lawmakers ? Democrats and Republicans alike ? who have balked at approving $1 billion in aid to Egypt that Obama promised in 2011 to help the new government settle an economic crisis that has drained the country's central bank and devalued the local currency in the revolution's aftermath.

"How would the American people feel about cutting money to education programs here and giving money to a government that is anti-Semitic?" Rep. Frank Wolf, R-Va., a member of the House Appropriations subcommittee that oversees funding to foreign governments, said.

"I don't think the administration has any right to say they are going to grant this foreign aid because I think this Congress may very well condition it," Wolf said. "I think there are a lot of questions, and I don't think it's a given."

Part of the proposed $1 billion aid package depends on International Monetary Fund approval of its own $4.8 billion loan to Egypt. But that loan has stalled for months because of Egypt's instability.

Despite its misgivings about Morsi, the White House still is pushing Congress for the funding, acknowledging that Egypt's downfall all but certainly would roil the already turbulent Mideast and North Africa.

"It's not in our interest to have an economic collapse in Egypt," said the senior Obama administration official.

The Brotherhood describes itself as a non-violent social organization dedicated to instilling Islamic values in the society. In Egypt, where it formed, the group was repressed by former regimes for decades and has struggled with adjusting to its new role leading the government. Its members, fearing a coup, are widely blamed with attacking anti-Morsi protesters outside the presidential palace in Cairo last month in clashes that left at least 10 people dead.

"What they missed was the fact that they are a governing party now, and to be getting into street battles when you also have commanding presence in the Egyptian state shows inexperience and panic," said Nathan Brown, a professor at George Washington University who has been researching Islamic movements for nearly a decade. "This is the kind of group that will be a pain to deal with for the United States, but it's not al-Qaida; it's not a security threat."

He added: "The biggest fear on the part of the (Obama) administration is a political breakdown in Egypt. They are worried that a collapse in the Egyptian state would be destabilizing on the region, and might allow the flow of arms and fighters among more radical movements in the region ? especially in trouble spots like Sinai and Gaza."

Obama administration officials said Morsi's promises to abide by Egypt's 1979 peace treaty with Israel, and continued security cooperation with Israel over the volatile Sinai Peninsula shows his willingness to be a reasonable partner. Morsi's work in November to broker a cease-fire between Israel and Gaza's Hamas rules was "a good first step," the senior Obama administration official said.

But Washington remains wary of Morsi and the Muslim Brotherhood, "who come from a very conservative viewpoint with issues that are very important to America," said Sen. Kirsten Gillibrand, D-N.Y.

Gillibrand was part of a delegation of U.S. lawmakers who met with Morsi in Cairo this month shortly after his 2010 statements surfaced. She stopped short of saying Morsi appeared chastened but described him as mindful of "how important America is to the viability of his presidency and the economy."

She said lawmakers want to see what actions he takes, "and we want to see if his words match those deeds and actions," Gillibrand said.

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Follow Lara Jakes on Twitter at https://twitter.com/larajakesAP

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/89ae8247abe8493fae24405546e9a1aa/Article_2013-01-28-US-Muslim%20Brotherhood/id-b7edbe6dd59240cab1f07fe62b6e5e8e

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#SciAmBlogs Monday - Kenyan mesopredators, Up-Goer Five, Commenting, #scio13, Historic Meteor Procession, Public Statistics, Davos, and more.


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Bora ZivkovicBora Zivkovic is the Blog Editor at Scientific American, chronobiologist, biology teacher, organizer of ScienceOnline conferences and editor of Open Laboratory anthologies of best science writing on the Web. Follow on Twitter @boraz. Bora ZivkovicBora Zivkovic is the Blog Editor at Scientific American, chronobiologist, biology teacher, organizer of ScienceOnline conferences and editor of Open Laboratory anthologies of best science writing on the Web. Follow on Twitter @boraz.

#SciAmBlogs Monday ? Kenyan mesopredators, Up-Goer Five, Commenting, #scio13, Historic Meteor Procession, Public Statistics, Davos, and more.

Bora ZivkovicAbout the Author: Bora Zivkovic is the Blog Editor at Scientific American, chronobiologist, biology teacher, organizer of ScienceOnline conferences and editor of Open Laboratory anthologies of best science writing on the Web. Follow on Twitter @boraz.

The views expressed are those of the author and are not necessarily those of Scientific American.

Source: http://rss.sciam.com/click.phdo?i=6b17903b4f6f855b68e025d851946f6a

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Monday, January 28, 2013

'Flipped Learning' Classroom Model Embraced By Teachers In Schools Nationwide

SANTA ANA, Calif. -- When Timmy Nguyen comes to his pre-calculus class, he's already learned the day's lesson ? he watched it on a short online video prepared by his teacher for homework.

So without a lecture to listen to, he and his classmates at Segerstrom Fundamental High School spend class time doing practice problems in small groups, taking quizzes, explaining the concept to other students, reciting equation formulas in a loud chorus, and making their own videos while teacher Crystal Kirch buzzes from desk to desk to help pupils who are having trouble.

It's a technology-driven teaching method known as "flipped learning" because it flips the time-honored model of classroom lecture and exercises for homework ? the lecture becomes homework and class time is for practice.

"It was hard to get used to," said Nguyen, an 11th-grader. "I was like `why do I have to watch these videos, this is so dumb.' But then I stopped complaining and I learned the material quicker. My grade went from a D to an A."

Flipped learning apparently is catching on in schools across the nation as a younger, more tech-savvy generation of teachers is moving into classrooms. Although the number of "flipped" teachers is hard to ascertain, the online community Flipped Learning Network now has 10,000 members, up from 2,500 a year ago, and training workshops are being held all over the country, said executive director Kari Afstrom.

Under the model, teachers make eight- to 10-minute videos of their lessons using laptops, often simply filming the whiteboard as the teacher makes notations and recording their voice as they explain the concept. The videos are uploaded onto a teacher or school website, or even YouTube, where they can be accessed by students on computers or smartphones as homework.

For pupils lacking easy access to the Internet, teachers copy videos onto DVDs or flash drives. Kids with no home device watch the video on school computers.

Class time is then devoted to practical applications of the lesson ? often more creative exercises designed to engage students and deepen their understanding. On a recent afternoon, Kirch's students stood in pairs with one student forming a cone shape with her hands and the other angling an arm so the "cone" was cut into different sections.

"It's a huge transformation," said Kirch, who has been taking this approach for two years. "It's a student-focused classroom where the responsibility for learning has flipped from me to the students."

The concept emerged five years ago when a pair of Colorado high school teachers started videotaping their chemistry classes for absent students.

"We found it was really valuable and pushed us to ask what the students needed us for," said one of the teachers, Aaron Sams, now a consultant who is developing on online education program in Pittsburgh. "They didn't need us for content dissemination, they needed us to dig deeper."

He and colleague Jonathan Bergmann began condensing classroom lectures to short videos and assigning them as homework.

"The first year, I was able to double the number of labs my students were doing," Sams said. "That's every science teacher's dream."

In the Detroit suburb of Clinton Township, Clintondale High School Principal Greg Green converted the whole school to flipped learning in the fall of 2011 after years of frustration with high failure rates and discipline problems. Three-quarters of the school's enrollment of 600 is low-income, minority students.

Flipping yielded dramatic results after just a year, including a 33 percent drop in the freshman failure rate and a 66 percent drop in the number of disciplinary incidents from the year before, Green said. Graduation, attendance and test scores all went up. Parent complaints dropped from 200 to seven.

Green attributed the improvements to an approach that engages students more in their classes.

"Kids want to take an active part in the learning process," he said. "Now teachers are actually working with kids."

Although the method has been more popular in high schools, it's now catching on in elementary schools, said Afstrom of the Flipped Learning Network.

Fifth-grade teacher Lisa Highfill in the Pleasanton Unified School District said for a lesson about adding decimals, she made a five-minute, how-to video kids watched at home and in class, then she distributed play money and menus and had kids "ordering" food and tallying the bill and change.

A colleague who teaches kindergarten reads a storybook on video. The video contains a pop-up box that requires kids to write something that shows they understood the story.

The concept has its downside. Teachers note that making the videos and coming up with project activities to fill class time is a lot of extra work up front, while some detractors believe it smacks of teachers abandoning their primary responsibility of instructing.

"They're expecting kids to do the learning outside the classroom. There's not a lot of evidence this works," said Leonie Haimson, executive director of Class Size Matters, a New York City-based parent advocacy group. "What works is reasonably sized classes with a lot of debate, interaction and discussion."

Others question whether flipped learning would work as well with low achieving students, who may not be as motivated to watch lessons on their own, but said it was overall a positive model.

"It's forcing the notion of guided practice," said Cynthia Desrochers, director of the Center for Excellence in Learning and Teaching at California State University-Northridge. "Students can get the easy stuff on their own, but the hard stuff should be under the watchful eye of a teacher."

At Michigan's Clintondale High School, some teachers show the video at the beginning of class to ensure all kids watch it and that home access is not an issue.

In Kirch's pre-calculus class, students said they liked the concept.

"You're not falling asleep in class, "said senior Monica Resendiz said. "You're constantly working."

Explaining to adults that homework was watching videos was a little harder, though.

"My grandma thought I was using it as an excuse to mess around on the Internet," Nguyen said.

___

Contact the reporter at . http://twitter.com/ChristinaHoag

Also on HuffPost:

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Source: http://www.huffingtonpost.com/2013/01/28/flipped-learning-classroo_n_2567279.html

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Coldfront ? This Week in NYC: Featured Readings

Sorry House Book ReleaseEvery week, Coldfront features five cross-borough readings in NYC. Here are this week?s picks.
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Boog City presents d.a. levy lives: celebrating the renegade press
Tuesday, January 29 @ 6:30 pm
Sidewalk Caf?, 94 Ave. A, New York, NY

$5 suggested

Event will be hosted by Hyacinth Girl editors Margaret Bashaar and Sarah Reck.

Curated and with an introduction by Boog City editor David Kirschenbaum.

Hyacinth Girl Press is a micro-press founded in 2011 that publishes poetry chapbooks. They specialize in handmade books of smaller press runs. They consider themselves a feminist press and are particularly interested in manuscripts dealing with topics such as radical spiritual experiences, creation/interpretation of myth through a feminist lens, and science. They think outer space, in particular, is pretty darn cool. Hyacinth Girl Press is edited by Margaret Bashaar and designed/laid out by Sarah Reck.

Margaret Bashaar?s second chapbook, Letters from Room 27 of the Grand Midway Hotel, was released by Blood Pudding Press in 2011. Her poetry has also appeared in or is forthcoming from journals such as Caketrain, Copper Nickel, Menacing Hedge, New South, and RHINO, among others. She edits Hyacinth Girl Press and lives in Pittsburgh with her husband, her son, and far too many typewriters.

Sarah Kain Gutowski?s poems have been published in Epiphany, So to Speak: A Feminist Journal, The Gettysburg Review, The Southern Review, The Threepenny Review, and Verse Daily. She keeps a record of her writing life, experience in academia, and motherhood at the above url.

Crystal J. Hoffman was raised by a biker and a truck driver in the woods outside of a dead mining town. This explains why her most important accomplishments to date are having been reprimanded for climbing trees on three continents and nearly freeing a monkey within one week of assuming her first full-time teaching post. Her poems have appeared in or are forthcoming in Arsenic Lobster, Redactions: Poetry and Poetics, Strange Horizons, Whiskey Island, and WomenArts Quarterly. She cofounded and directed the TypewriterGirls Poetry Cabaret with Hyacinth Girl Press editor Margaret Bashaar for five years and spent the past year inducing the Cabaret Voltaire spirit in the Middle East while teaching creative writing at the American University of Beirut.

Niina Pollari wrote two chapbooks, Book Four (Hyacinth Girl Press) and Fabulous Essential (Birds of Lace). A full-length translation of the work of Tytti Heikkinen is due out from Action Books in spring 2013.

Sarah Reck?s short stories have appeared in Elephant Tree and The Tributary. She is co-founding and managing editor of Litterbox Magazine (on hiatus), and blogs at the above url. She lives in New York City and works as a web publicist for a major publishing house.

J. Hope Stein is the author of [Talking Doll] (Dancing Girl Press), [Mary] (Hyacinth Girl Press), and Corner Office (H_ngm_n Bks). She is the editor of Poetry Crush.

Boog City is a New York City-based small press now in its 22nd year and East Village community newspaper of the same name. It has put out approximately 200 publications, including 35 volumes of poetry and various magazines and a newspaper, featuring work by Allen Ginsberg and Lawrence Ferlinghetti among others, and theme issues on baseball, women?s writing, and Louisville, Ky. It hosts and curates three regular performance series?d.a. levy lives: celebrating the renegade press, featuring a non-NYC small press, its writers, and a musical act; the new BoogWork series, which features two poets reading, followed by a musical performance, and then the featured poet giving the gathered a poetry workshop; and Classic Albums Live, where up to 13 local musical acts perform a classic album live. Past albums have included Elvis Costello, My Aim is True; Nirvana, Nevermind; Sleater-Kinney?s, Dig Me Out; and Liz Phair, Exile in Guyville. All of these series are hosted at Sidewalk Cafe.

and music from
mindtroll
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Fledge: A Tribute to Stacy Doris
Wednesday, January 30th @ 8pm
The Poetry Project, 131 E. 10th Street, New York, NY

Join us at The Poetry Project for readings of work by internationally acclaimed poet and translator Stacy Doris, with special attention to her final book?Fledge?(Nightboat Books). Doris?s previous books of poetry in English are?Kildare, Paramour, Conference, Knot, Cheerleader?s Guide to the World: Council Book, and?The Cake Part. She also wrote three books in French and translated three volumes of French poetry into English. She died on January 31, 2012 at her home in San Francisco, where she taught in the Creative Writing Programs at SFSU. With?Chet Wiener, James Sherry, Lee Ann Brown, Rob Fitterman, Kim Rosenfield, Nada Gordon, Jena Osman, Ann Lauterbach, Cole Swensen, Laynie Browne, Charles Bernstein, Carol Mirakove, Julie Regan and Daria Fain.
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Sorry House Book Release
Thursday, January 31st @ 7pm
Housing Works Bookstore, 126 Crosby Street, New York, NY

Poet Mira Gonzalez is joined by Kool A.D., Giancarlo DiTrapano, Spencer Madsen, Melissa Broder, Willis Plummer, and Marshall Mallicoat for a reading & celebration. Drinks, books, limited-run zines & prints will all be available.

Sorry House?is a Brooklyn-based independent publisher of books in print. The first title?I will never be beautiful enough to make us beautiful together?by Mira Gonzalez will be released and sold for the first time at Housing Works Bookstore Cafe on January 31st.

All proceeds benefit Housing Works.

Flyer by?Erik Carter.
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Brenda Shaughnessy and Craig Morgan Teicher
Friday, February 1st @ 5 pm
Lillian Vernon Creative Writers House, 58 West 10th St, New York, NY

Brenda Shaughnessy?s new collection is Our Andromeda (Copper Canyon Press, 2012). To Keep Love Blurry, Craig Morgan Teicher?s latest title, was published by BOA Editions in 2012.

Sponsored by NYU Creative Writing Program
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The Death and Life of American Cities
Friday, February 1st @ 10pm
The Poetry Project, 131 E. 10th Street, New York, NY

In the tradition of?Floating Bear,?Try!,?Rolling Stock?and other hyperactive journals before it,?The Death and Life of American Cities?is couched in the necessity of materializing writing?s frequency in all its cantering grime.? Please join us for a one night procedural intervention in this circuit to parse the first 10 months of publication/gestation with readings by?erica kaufman, Jennifer Nelson, Jamie Townsend, Andrew Durbin, Josef Kaplan and others.

Liquor will flow (though you may want to bring forth from the earth, etc); myna birds will sing; there will, with god?s grace, be karaoke.

And, of course, the new Death and Life of American Cities will be available.
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Have a listing for consideration? Email stephanie.whited(at)gmail(dot)com.

Source: http://coldfrontmag.com/news/nyc-featured-readings-3

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Obama: Media Is 'One Of The Biggest Factors' Shaping Debates

  • Mr. President

    U.S. President Barack Obama waves as the presidential inaugural parade winds through the nation's capital January 21, 2013 in Washington, D.C. (Photo by Mark Wilson/Getty Images)

  • Mr. Vice President

    U.S. Vice President Joe Biden and his wife Dr. Jill Biden walk along Pennsylvania Avenue during the parade following Obama's second inauguration as the 44th U.S. president on January 21, 2013 in Washington, D.C. (JOE KLAMAR/AFP/Getty Images)

  • The First Couple

    President and Michelle Obama wave to onlookers as the presidential inaugural parade winds through the nation's capital January 21, 2013 in Washington, D.C. (Photo by Chip Somodevilla/Getty Images)

  • Right In Our Backyard

    U.S. President Barack Obama and First lady Michelle Obama walk past the reviewing stand as the presidential inaugural parade winds through the nation's capital January 21, 2013 in Washington, D.C. (Photo by Mark Wilson/Getty Images)

  • Parade Pandemonium

    U.S. President Barack Obama drives down Pennsylvania avenue in his vehicle during the Inauguration Parade on January 21, 2013 in Washington, D.C. (Photo by Joe Raedle/Getty Images)

  • Secret Service Security

    A U.S. Secret Service vehicle escorts President Barack Obama and First Lady Michelle Obama's motorcade during the inauguration parade on January 21, 2013 in Washington, D.C. (Photo by John Moore/Getty Images)

  • Obama's Wheels

    WASHINGTON, DC - JANUARY 21: U.S. President Barack Obama drives down Pennsylvania avenue in his vehicle during the Inauguration Parade on January 21, 2013 in Washington, DC. The President was sworn in for second term. (Photo by Joe Raedle/Getty Images)

  • Awaiting Obama's Arrival

    People watch as the presidential inaugural parade winds through the nation's capital January 21, 2013 in Washington, D.C. (Photo by Justin Sullivan/Getty Images)

  • Showtime

    U.S. President Barack Obama exits his limousine to walk during a portion of the presidential inaugural parade in the nation's capital January 21, 2013 in Washington, D.C. (Photo by Win McNamee/Getty Images)

  • A Walk Back In Time

    Men in traditional colonial garb perform as U.S. President Barack Obama and First Lady Michelle Obama walk along Pennsylvania Avenue during the parade following Obama's second inauguration as the 44th US president on January 21, 2013 in Washington, D.C.(MLADEN ANTONOV/AFP/Getty Images)

  • A Hearty Thank You

    President Barack Obama waves after taking the oath of office during the 57th Presidential Inauguration ceremonial swearing-in at the U.S. Capitol on January 21, 2013 in Washington, D.C. (JEWEL SAMAD/AFP/Getty Images)

  • The President's Pen

    U.S. President Barack Obama (4R) is surrounded by (L-R) Senate Majority Leader Sen. Harry Reid (D-NV), Sen. Lamar Alexander (R-TN), Sen. Chuck Schumer (D-NY), Vice President Joe Biden, House Speaker Rep. John Boehner (R-OH), House Majority Leader Rep. Eric Cantor (R-VA) and House Minority Leader Rep. Nancy Pelosi (D-CA) while signing a proclamation to commemorate the inauguration, entitled a National Day of Hope and Resolve, directly after swearing-in ceremonies in the U.S. Capitol on January 21, 2013 in Washington, D.C. (Photo by Jonathan Ernst-Pool/Getty Images)

  • Putting It In Writing

    President Barack Obama (2L) signs a proclamation to commemorate the inauguration, entitled a National Day of Hope and Resolve, as (L-R) Vice President Joe Biden, House Speaker Rep. John Boehner (R-OH), and House Majority Leader Rep. Eric Cantor (R-VA) look on directly after swearing-in ceremonies in the U.S Capitol on January 21, 2013 in Washington, D.C. (Photo by Jonathan Ernst-Pool/Getty Images)

  • It's Official

    President Barack Obama is sworn by Chief Justice John Roberts at the ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • The National Anthem

    President Barack Obama, surrounded by members of his family, listens to the National Anthem during the 57th Presidential Inauguration ceremonial swearing-in at the U.S. Capitol on January 21, 2013 in Washington, D.C. (JEWEL SAMAD/AFP/Getty Images)

  • The Winning Ticket

    U.S. President Barack Obama (L) talks with U.S. Vice President Joe Biden on the reviewing stand as the presidential inaugural parade winds through the nation's capital January 21, 2013 in Washington, D.C. (Photo by Mark Wilson/Getty Images)

  • Husband And Wife

    President Barack Obama takes the oath of office during the 57th Presidential Inauguration ceremonial swearing-in at the U.S. Capitol on January 21, 2013 in Washington, D.C. (JEWEL SAMAD/AFP/Getty Images)

  • Father And Daughters

    President Barack Obama is greeted by daughter Sasha as Malia looks on at the beginning of the 57th Presidential Inauguration ceremonial swearing-in at the US Capitol on January 21, 2013 in Washington, D.C. (JEWEL SAMAD/AFP/Getty Images)

  • Sister, Sister

    First daughters Sasha (L) and Malia arrive for the 57th Presidential Inauguration ceremonial swearing-in of President Barack Obama at the U.S. Capitol on January 21, 2013 in Washington, D.C. (JEWEL SAMAD/AFP/Getty Images)

  • The Second Family

    Vice President Joe Biden and his wife Dr. Jill Biden attend the Inaugural Luncheon in Statuary Hall on Inauguration day at the U.S. Capitol building January 21, 2013 in Washington D.C. (Photo by Allison Shelley/Getty Images)

  • Bill & Hillary

    Former president Bill Clinton and the current U.S. Secretary of State Hillary Clinton arrive for the 57th Presidential Inauguration ceremonial swearing-in of President Barack Obama at the U.S. Capitol on January 21, 2013 in Washington, D.C. (JEWEL SAMAD/AFP/Getty Images)

  • Hillary & Harry

    Former U.S. President Bill Clinton, Secretary of State Hillary Clinton and Senate Majority Leader Harry Reid, applaud during the Inaugural Luncheon in Statuary Hall on inauguration day at the U.S. Capitol building January 21, 2013 in Washington D.C. (Photo by Allison Shelley/Getty Images)

  • The Supreme Court

    U.S. Supreme Court Justices (L-R) Anthony Kennedy, Supreme Court Chief Justice John Roberts, Clarence Thomas, Sonia Sotomayor Elena Kegan, Samuel A. Alito, and Stephen G. Breyer attend the presidential inauguration on the West Front of the U.S. Capitol January 21, 2013 in Washington, D.C. (Photo by John Moore/Getty Images)

  • Let's Do Lunch

    President Barack Obama shakes hands as he and first lady Michelle Obama arrive at the Inaugural Luncheon in Statuary Hall on Inauguration day at the U.S. Capitol building January 21, 2013 in Washington D.C. (Photo by Allison Shelley/Getty Images)

  • Fine Dining

    The place card for U.S. President Barack Obama sits ready for the Inaugural Luncheon in Statuary Hall on inauguration day at the U.S. Capitol building January 21, 2013 in Washington D.C. (Photo by Allison Shelley/Getty Images)

  • Neatly-Folded Napkins

    Rocio Saucedo of Design Cuisine folds napkins in preparation for the Inaugural Luncheon in Statuary Hall on Inauguration day at the U.S. Capitol building January 21, 2013 in Washington D.C. (Photo by Allison Shelley/Getty Images)

  • Time To Eat

    Caterers set up for the Inaugural Luncheon in Statuary Hall on Inauguration day at the U.S. Capitol building January 21, 2013 in Washington D.C. (Photo by Allison Shelley/Getty Images)

  • Crystal Clear

    U.S. Sen. Chuck Schumer (D-NY), chairman of the Joint Congressional Committee on Inaugural Ceremonies, holds a crystal vase during a media briefing at the U.S. Capitol January 18, 2013 in Washington, D.C. (Photo by Mark Wilson/Getty Images)

  • A Toast

    U.S. Vice President Joe Biden toasts with Sen. Charles Schumer, Chairman of the Joint Congressional Committee on Inaugural Ceremonies, at the Inaugural Luncheon in Statuary Hall on inauguration day at the U.S. Capitol building January 21, 2013 in Washington D.C. (Photo by Allison Shelley/Getty Images)

  • Capitol Pomp And Circumstance

    President Barack Obama gives his speech after taking the oath of office during the 57th Presidential Inauguration ceremonial swearing-in at the U.S. Capitol on January 21, 2013 in Washington, D.C. (JEWEL SAMAD/AFP/Getty Images)

  • The National Mall

    People crowd the National Mall to view U.S. President Barack Obama taking the oath of office during the 57th Presidential Inauguration ceremonial swearing-in at the U.S. Capitol on January 21, 2013 in Washington, D.C. (SAUL LOEB/AFP/Getty Images)

  • The Presidential Motorcade

    The presidential motorcade travels down Pennsylvania Ave. during the presidential inauguration January 21, 2013 in Washington, D.C. (Photo by John Moore/Getty Images)

  • Take Your Seats

    Reserved seats for guests to view U.S. President Barack Obama taking the oath of office during the 57th Presidential Inauguration ceremonial swearing-in at the US Capitol on January 21, 2013 in Washington, D.C. (SAUL LOEB/AFP/Getty Images)

  • The Podium

    Placemarks are set for the Obama and Biden families before the presidential inauguration on the West Front of the U.S. Capitol January 21, 2013 in Washington, D.C. (Photo by Win McNamee/Getty Images)

  • Places, Please!

    Placemarks are set for the Obama and Biden families before the presidential inauguration on the West Front of the U.S. Capitol January 21, 2013 in Washington, D.C. (Photo by Win McNamee/Getty Images)

  • A Special Sunrise

    American flags are waved as people gather near the U.S. Capitol building on the National Mall for the Inauguration ceremony on January 21, 2013 in Washington, D.C. (Photo by Joe Raedle/Getty Images)

  • The Gingrich Family

    Former House Speaker Newt Gingrich and wife Callista Gingrich arrive during the presidential inauguration on the West Front of the U.S. Capitol January 21, 2013 in Washington, D.C. (Photo by John Moore/Getty Images)

  • You Go, Joe

    President Barack Obama, center and Beau Biden, Attorney of Deleware, right, watch as his father Joe Biden is sworn in at the ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • Any Minute Now

    President Barack Obama and Vice President Joe Biden look behind them on the West Front of the Capitol in Washington, Monday, Jan. 21, 2013, before their ceremonial swearing-in ceremony during the 57th Presidential Inauguration.

  • A Room With A View

    Vice President Joe Biden, left and President Barack Obama wait for their ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • I'm Here

    Caption contest, Anyone? Vice President Joe Biden, followed by House Minority Leader Nancy Pelosi of Calif., arrives on the West Front of the Capitol in Washington, Monday, Jan. 21, 2013, for the Presidential Barack Obama's ceremonial swearing-in ceremony during the 57th Presidential Inauguration.

  • All Smiles

    Flanked by Sen. Charles Schumer, D-N.Y., President Barack Obama and Vice President Joe Biden arrive at the ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • The Team

    President Barack Obama greets Vice President Joe Biden at the ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • Hillary Greets President Obama

    President Barack Obama is greeted by Secretary of State Hillary Clinton and former President Bill Clinton for his ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • The President Arrives

    President Barack Obama arrives for his ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • Bill 'Photo Bombs' Joe

    Vice President Joe Biden arrives at the ceremonial swearing-in of President Barack Obama at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013. Right is former President Bill Clinton.

  • Thumbs Up

    President Barack Obama flashes a thumbs up at the ceremonial swearing-in at the U.S. Capitol during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013.

  • President Obama Salutes

    This handout photo provided by NASA shows President Barack Obama saluting as he and Sen. Charles Schumer, D-N.Y., chairman of the Joint Congressional Committee on Inaugural Ceremonies, depart the White House for Capitol Hill in Washington, Monday, Jan. 21, 2013, and Obama's ceremonial swearing-in ceremony during the 57th Presidential Inauguration.

  • Hillary & Bill Arrive On The West Front

    Secretary of State Hillary Rodham Clinton and former President Bill Clinton arrive on the West Front of the Capitol in Washington, Monday, Jan. 21, 2013, for the Presidential Barack Obama's ceremonial swearing-in ceremony during the 57th Presidential Inauguration.

  • Even McCain Is Fired Up

    Sen. John McCain, R-Ariz. arrives on the West Front of the Capitol in Washington, Monday, Jan. 21, 2013, for the Presidential Barack Obama's ceremonial swearing-in ceremony during the 57th Presidential Inauguration.

  • Leon Panetta Arrives

    Defense Secretary Leon Panetta and Transportation Secretary Ray LaHood arrive on the West Front of the Capitol in Washington, Monday, Jan. 21, 2013, for the Presidential Barack Obama's ceremonial swearing-in ceremony during the 57th Presidential Inauguration.

  • Source: http://www.huffingtonpost.com/2013/01/27/obama-media_n_2560269.html

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    Thursday, January 24, 2013

    Modifications of a nanoparticle can change chemical interactions with cell membranes

    Jan. 23, 2013 ? Researchers at Syracuse University's Department of Biomedical and Chemical Engineering at L.C. Smith College of Engineering and Computer Science are studying the toxicity of commonly used nanoparticles, particles up to one million times smaller than a millimeter that could potentially penetrate and damage cell membranes.

    In a recent article published along with cover art in the journal Langmuir, researchers Shikha Nangia, assistant professor of biomedical and chemical engineering (BMCE), and Radhakrishna Sureshkumar, Department Chair of BMCE and professor of physics, showed how simple shape and charge modifications of a nanoparticle can cause tremendous changes in the chemical interactions between the nanoparticle and a cell membrane.

    Nanomaterials, which are currently being used as drug carriers, also pose a legitimate concern, since no universal standards exist to educate and fully protect those who handle these materials. Nanoparticles are comparable to chemicals in their potential threat because they could easily penetrate the skin or be inhaled.

    "Nanotechnology has immense potential that is starting to be being realized; a comprehensive understanding of toxicity of nanoparticles will help develop better safe handling procedures in nanomanufacturing and nano-biotechnology" says Sureshkumar and Nangia, In addition, the toxicity levels of various nanoparticles can be used to our advantage in targeting cancer cells and absorbing radiation during cancer therapy. Nanotoxicity is becoming a major concern as the use of nanoparticles in imaging, therapeutics, diagnostics, catalysis, sensing and energy harvesting continues to grow dramatically.

    This research project has taken place over the past year utilizing a state of the art 448 core parallel computer nicknamed "Prophet" housed in Syracuse University's Green Data Center. The research was funded by the National Science Foundation.

    Langmuir is a notable, interdisciplinary journal of American Chemical Society publishing articles in: colloids, interfaces, biological interfaces, nano-materials, electrochemistry and devices and applications.

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    Story Source:

    The above story is reprinted from materials provided by Syracuse University.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. Shikha Nangia, Radhakrishna Sureshkumar. Effects of Nanoparticle Charge and Shape Anisotropy on Translocation through Cell Membranes. Langmuir, 2012; 28 (51): 17666 DOI: 10.1021/la303449d

    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/top_health/~3/XVzlBAkegHQ/130123165103.htm

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    Video: Obama?s address labeled ?too liberal? by the right

    N. Korea's propaganda poets stay true to their muse

    Official pronouncements from North Korea?s state-controlled media have always had a poetic quality -- albeit angry and paranoid. More than a year after Kim Jong Un came to power, Pyongyang remains pleased with its rhetoric, despite mocking laughter from the rest of the world.

    Source: http://video.msnbc.msn.com/hardball/50566667/

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    Wednesday, January 23, 2013

    New strategy to fight deadly infection in cystic fibrosis

    Jan. 23, 2013 ? New research suggests that lowering excessive levels of a protein in immune system cells could be a strategy to clear an infection that is deadly to patients with cystic fibrosis (CF).

    Researchers determined that normalizing levels of the protein, called p62, in cells from mice carrying the most common mutation that causes CF will jump-start a natural cellular process that clears away the offending bacteria.

    The scientists had previously determined that in cells from mice and humans carrying the CF mutation, the bacteria that cause this infection interfere with an important survival process in immune system cells; they also attributed this interference to elevated levels of p62.

    The survival process, called autophagy, allows a cell to digest parts of itself to produce energy when it is experiencing starvation. In many infections, autophagy also helps digest pathogens and clear them away.

    The bacterium, Burkholderia cenocepacia, causes a severe and persistent lung infection in patients with CF and is resistant to nearly all known antibiotics. Various types of chronic lung infection are responsible for about 85 percent of deaths in CF patients.

    "Autophagy also controls inflammation, so when you decrease p62 levels in a CF mouse model and that improves autophagy, you are controlling inflammation produced by Burkholderia cenocepacia. And that's what we are trying to do for patients -- save them from inflammation," said Amal Amer, associate professor of microbial infection and immunity and internal medicine at Ohio State University and senior author of the study.

    While relatively rare, B. cenocepacia infection is highly transmissible in patients with cystic fibrosis. By causing either severe sepsis or massive inflammation that damages lung tissue, the infection amounts to a death sentence for CF patients.

    To lower p62 levels, the researchers introduced a small interfering RNA molecule, or siRNA, to silence a specific gene and reduce the protein's activation. Amer plans to next test this protein-lowering technique in mice that are models for cystic fibrosis. Designing a similar strategy in humans would require many years of additional study, she noted.

    The study is published in the current issue of the Journal of Biological Chemistry.

    The cells that can use autophagy to clear infection are macrophages, which are first responders in the immune system that consume offending pathogens.

    In previous work, Amer and former Ohio State doctoral student Basant Abdulrahman showed that in macrophages isolated from both mice and humans that carried the most common CF mutation, the bacterium would invade the macrophage and thrive instead of being digested and cleared away as it was in cells without the mutation.

    The research group showed that rapamycin, an existing drug known to stimulate autophagy, helped control B. cenocepacia infection in mice that serve as a model for cystic fibrosis.

    "Rapamycin worked well as a proof of concept, but it has so many side effects that it's hard to imagine giving it to small children with CF for an extended period of time. That's why we looked for another method," said Amer, also an investigator in Ohio State's Center for Microbial Interface Biology (CMIB).

    For this study, the researchers conducted experiments in macrophage cells derived from mice carrying the CF mutation and compared them to macrophages from normal, healthy mice.

    The researchers observed in macrophages with the mutation that when p62 is elevated, other cell components clump together, causing disruption to the autophagy process.

    "p62 is a sticky protein, so high levels of it lead to the formation of aggregates. Once we get rid of that sticky protein -- the glue -- these protein aggregates will be able to go where they are supposed to go and allow the autophagy process to work properly," Amer said.

    Abdulrahman observed that in cells with the CF mutation, a key molecule gets caught up in those clumps. This molecule, beclin1, has a critical autophagy job, essentially escorting foreign particles to the cell parts that digest them and clear them away.

    "Our hypothesis was that if we downregulate p62, this will release beclin1 from the aggregates. Once it's available, we will have active autophagic machinery that is able to control the infection," said Abdulrahman, first author on the paper.

    In contrast, lowering p62 in macrophages from normal mice allowed the B. cenocepacia bacteria to grow. This confirmed that p62 actually controls the infection in cells from healthy animals but has the opposite effect when the CF mutation is present, she said.

    This work is supported by the National Institutes of Health, Cystic Fibrosis Canada and an Egyptian Bureau of Education fellowship.

    Additional co-authors are Arwa Abu Khweek, Kyle Caution, Mia Tazi, Hoda Hassan, Yucheng Zhang; Sankalp Malhotra and Patrick Rowland of the Department of Microbial Infection and Immunity, Department of Internal Medicine and CMIB; and Famke Aeffner and Ian Davis of the Medical Scientist Training Program and Department of Veterinary Biosciences, all at Ohio State; and Miguel Valvano of the University of Western Ontario and Queen's University.

    Share this story on Facebook, Twitter, and Google:

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    Story Source:

    The above story is reprinted from materials provided by Ohio State University, via Newswise.

    Note: Materials may be edited for content and length. For further information, please contact the source cited above.


    Journal Reference:

    1. B. A. Abdulrahman, A. A. Khweek, A. Akhter, K. Caution, M. Tazi, H. Hassan, Y. Zhang, P. D. Rowland, S. Malhotra, F. Aeffner, I. C. Davis, M. A. Valvano, A. O. Amer. Depletion of the Ubiquitin-binding Adaptor Molecule SQSTM1/p62 from Macrophages Harboring cftr ?F508 Mutation Improves the Delivery of Burkholderia cenocepacia to the Autophagic Machinery. Journal of Biological Chemistry, 2012; 288 (3): 2049 DOI: 10.1074/jbc.M112.411728

    Note: If no author is given, the source is cited instead.

    Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

    Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/nXyOa3KHrek/130123114226.htm

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    Exit polls: Netanyahu narrowly wins Israel vote

    JERUSALEM (AP) ? Prime Minister Benjamin Netanyahu and his hard-line allies fared far worse than expected in a parliamentary election Tuesday, preliminary results showed, likely forcing him to reach across the aisle to court a popular political newcomer to cobble together a new coalition.

    While Netanyahu appeared positioned to serve a third term as prime minister, the results marked a major setback for his policies and could force him to make new concessions to restart long-stalled peace talks with the Palestinians.

    Over 95 percent of the votes were counted by Wednesday morning and the hawkish and dovish blocs were split about evenly.

    Netanyahu's most likely partner was Yesh Atid, or There is a Future, a party headed by political newcomer Yair Lapid that showed surprising strength. Lapid has said he would only join a government committed to sweeping economic changes and a resumption of peace talks with the Palestinians.

    Addressing his supporters early Wednesday, Netanyahu vowed to form as broad a coalition as possible. He said the next government would be built on principles that include reforming the contentious system of granting draft exemptions to ultra-Orthodox Jewish men and the pursuit of a "genuine peace" with the Palestinians. He did not elaborate, but the message seemed aimed at Lapid.

    Shortly after the results were announced, Netanyahu called Lapid and offered to work together. "We have the opportunity to do great things together," Netanyahu was quoted as saying by Likud officials.

    According to preliminary results, Netanyahu's Likud-Yisrael Beitenu alliance was set to capture about 31 of the 120 seats, significantly fewer than the 42 it held in the outgoing parliament and below the forecasts of recent polls.

    With his traditional allies of nationalist and religious parties, Netanyahu could put together a shaky majority of 61 seats, initial results showed. But it would be virtually impossible to keep such a narrow coalition intact, though it was possible he could take an additional seat or two as numbers trickled in throughout the night.

    The results capped a lackluster campaign in which peacemaking with the Palestinians, traditionally the dominant issue in Israeli politics, was pushed aside. Netanyahu portrayed himself as the only candidate capable of leading Israel at a turbulent time, while the fragmented opposition targeted him on domestic economic issues.

    Netanyahu's goal of a broader coalition will force him to make some difficult decisions. Concessions to Lapid, for instance, will alienate his religious allies. In an interview last week with The Associated Press, Lapid said he would not be a "fig leaf" for a hard-line, extremist agenda.

    Lapid's performance was the biggest surprise of the election. The one-time TV talk show host and son of a former Cabinet minister was poised to win 19 seats, giving him the second-largest faction in parliament.

    Presenting himself as the defender of the middle class, Lapid vowed to take on Israel's high cost of living and to end the contentious system of subsidies and draft exemptions granted to ultra-Orthodox Jews while they pursue religious studies. The expensive system has bred widespread resentment among the Israeli mainstream.

    Thanks to his strong performance, Lapid is now in a position to serve as the kingmaker of the next government. He will likely seek a senior Cabinet post and other concessions.

    Yaakov Peri, a member of Lapid's party, said it would not join unless the government pledges to begin drafting the ultra-Orthodox into the military, lowers the country's high cost of living and returns to peace talks. "We have red lines. We won't cross those red lines, even if it will cost us sitting in the opposition," Peri told Channel 2 TV.

    Addressing his supporters, a beaming Lapid was noncommittal, calling only for a broad government with moderates from left and right. "Israelis said no to the politics of fear and hatred," he said. "And they said no to extremism and anti-democracy."

    There was even a distant possibility of Lapid and more dovish parties teaming up to block Netanyahu from forming a majority.

    "It could be that this evening is the beginning for a big chance to create an alternative government to the Netanyahu government," said Shelly Yachimovich, leader of the Labor Party, which won 15 seats on a platform pledging to narrow the gaps between rich and poor.

    Although that seemed unlikely, Netanyahu clearly emerged from the election in a weakened state.

    "We expected more seats in the parliament," Danny Danon, a senior Likud member, told the AP. "But the bottom line is that Benjamin Netanyahu is the next prime minister of Israel."

    Under Israel's system of proportional representation, seats in the 120-member parliament are allocated according to the percentage of votes a party gets. As leader of the largest party, Netanyahu is in the best position to form a coalition and be prime minister.

    The results were shocking, given the steady stream of recent opinion polls forecasting a solid victory by Netanyahu and his allies. Netanyahu appeared to suffer because of his close ties to the ultra-Orthodox and perhaps from complacency. Many voters chose smaller parties, believing a Netanyahu victory was inevitable.

    Tensions with the United States, Israel's most important ally, also may have factored into the thinking. President Barack Obama was quoted last week as saying that Netanyahu was undermining Israel's own interests by continuing to build Jewish settlements on occupied lands.

    Netanyahu has won praise at home for drawing the world's attention to Iran's suspect nuclear program and for keeping the economy on solid ground at a time of global turmoil. In his speech, Netanyahu said that preventing Iran from developing nuclear weapons would remain his top priority.

    But internationally, he has repeatedly clashed with allies over his handling of the peace process.

    Peace talks with the Palestinians have remained stalled throughout his term, in large part because of his continued construction of Jewish settlements in the West Bank and east Jerusalem. The Palestinians want a halt to settlement construction before talks begin. Netanyahu says talks must start without any preconditions.

    Obama has had a turbulent relationship with Netanyahu, and the two leaders could find themselves on a collision course in their new terms. The Obama administration said that regardless of the results of the election, the U.S. approach to the conflict would not change.

    "We will continue to make clear that only through direct negotiations can the Palestinians and the Israelis ... achieve the peace they both deserve," said White House spokesman Jay Carney.

    In London, British Foreign Secretary William Hague urged Obama to make the Middle East peace process his top priority. "We are approaching the last chance to bring about such a solution," Hague warned.

    Netanyahu himself has only grudgingly voiced conditional support for a Palestinian state, and his own party is now dominated by hard-liners who oppose even that. A potential coalition partner, Naftali Bennett of the Jewish Home Party, which won 11 seats, has called for annexing large parts of the West Bank, the core of any future Palestinian state.

    While Lapid advocates a softer line toward the Palestinians, his campaign focused on economic issues and it remains unclear how hard he will push Netanyahu on the issue.

    Lapid's positions also fall short of Palestinian demands. Most critically, he opposes any division of Jerusalem. The Palestinians seek the West Bank, Gaza Strip and east Jerusalem, territories captured by Israel in the 1967 Mideast war, for a future state.

    The Palestinians viewed the election results grimly.

    "If he brings Lapid into his government, this would improve the image of the Netanyahu government in the eyes of the world. But it won't make him stop building settlements, particularly in east Jerusalem," said Mohammed Ishtayeh, a senior adviser to President Mahmoud Abbas.

    In all, 32 parties contested the election, and 12 won enough votes to enter parliament, according to the exit polls. Netanyahu now has up to six weeks to form a government.

    By early Wednesday, the official Election Commission had published results of about half the ballots. Full results were expected later in the day.

    ___

    Aron Heller in Tel Aviv, Daniel Estrin and Ian Deitch in Jerusalem, and Mohammed Daraghmeh in Ramallah, West Bank, contributed to this report.

    Source: http://news.yahoo.com/exit-polls-netanyahu-narrowly-wins-israel-vote-222249719.html

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    Seeking `Higher' Ground: The Dangers of Designer Drugs

    Since ancient times, humans have been fascinated with ways to alter consciousness, and have gone to great lengths to reach a "higher" ground. From naturally occurring substances such as opium and betel nuts, to synthetic drugs like LSD, people have long experimented with mind-altering substances. This long history of experimentation with psychoactive substances even pre-dates the existence of the word "drug."

    For example, Native Americans' use of mescaline, extracted from peyote cacti, began as long as 5,700 years ago. Use of the Betel nut - the seed of a palm tree fruit - to alter consciousness may not be well-known in the U.S., but this practice has existed for thousands of years. In fact, it is estimated that among intoxicants, only nicotine, alcohol and caffeine are more popular globally than chewing Betel nut extract.

    But the latest wave of man-made drugs, or "designer drugs," carries new and very real dangers. For both the individuals using them and the general public, so-called designer drugs like "bath salts," "K2" or "spice" quickly have become a public health crisis, and their use is on the rise. Their danger is related to the potent effect these drugs can have on the human nervous system. For example, "bath salts" (chemically known as synthetic cathinones) combine the dangerous properties of both a potent stimulant and a hallucinogen. "K2" is a type of synthetic marijuana (the active compound is THC) and is dangerous because it can be more potent than the naturally occurring plant.

    These new designer drugs are proliferating because in many states they are sold "legally." This is possible because they are deliberately designed with an alteration to the molecular structure of an existing drug -- to avoid classification as an illicit drug.

    Despite their recent proliferation, "designer drugs" are not really new - the term was coined by law enforcement in the 1980s, and widely recognized drugs like LSD, ecstasy and methamphetamines fall into this category. The latest generation of designer drugs includes synthetic cathinones (commonly labeled with harmless-sounding monikers like "bath salts" or "plant food"), which are structurally and pharmacologically similar to cocaine, methamphetamines and ecstasy (MDMA). Synthetic cannabinoids, often branded as "Spice" or "K2," are chemically engineered to mimic marijuana. There are many other potent designer drugs with names like Europa and Smiles that are increasing in use. Many of these designer drugs are available legally in drug paraphernalia stores, convenience stores or even via the Internet. That's right, legally. Like many cyber sales, delivered to your door with free shipping.

    Law enforcement officials are increasing efforts to monitor for and curtail the use of these dangerous drugs. For example, the Drug Enforcement Administration (DEA) now includes three synthetic cathinones on its Schedule 1 list of controlled substances and several of the chemicals found in synthetic cannabinoids are banned under the Food and Drug Administration Safety and Innovation Act of 2012. But many similar compounds are not yet classified as illegal and in some cases they have not even been identified. This is because the "chemists" who produce designer drugs make incremental alterations to the drugs' chemical make-up, dodging Schedule 1 or illegal classification on a technicality, and thereby claiming to provide a "legal" high.

    For law enforcement officials and regulators, keeping up with these chemists is a game of cat-and-mouse, with potentially deadly consequences. Bath salts carry a high risk of overdose and addiction, chest pains, increased blood pressure, increased heart rate, agitation, hallucinations, extreme paranoia, and delusions1. Reported side effects of K2 and Spice include paranoia, panic attacks, giddiness and psychotic episodes.2 Despite these risks, their use is on the rise at an alarming rate. In 2011, the National Poison Control Centers received more than 6,000 calls about synthetic cathinones (including bath salts), compared to only 300 in 20103. The American Association of Poison Control Calls reported a 58 percent increase in the number of calls related to synthetic marijuana and/or K2/Spice in just one year - from 2,906 calls in 2010 to 6,959 calls in 2011.4 To make matters worse, the popularity of these drugs is fueled by the frequent claim that standard urine drug screens will not detect their presence. Luckily, there is a new solution that can detect these substances. Sophisticated laboratory technologies using mass spectrometry assays of urine specimens can identify the vast majority of legal and illegal drugs ingested, since most small molecules have metabolites (i.e., break down products) that are excreted by the kidneys and into the urine. Mass spectrometry assays currently used to detect and monitor use of powerful pain medications (e.g. opioids) can be mobilized to help physicians and regulators, such as the DEA, detect these new designer drugs. Specialty laboratories are using these advanced technologies to anticipate new chemical formulations and launch new tests to detect dangerous substances. For example, long before bath salts were a problem in the U.S., the United Kingdom was struggling with increasing rates of overdose and death due to synthetic cathinones. Reports from British physicians, and the laboratory scientists, prompted U.S.-based scientists to develop new tests that would detect multiple synthetic cathinones - even variations that were not yet classified by DEA as Schedule 1 substances. Because physicians are on the front lines - typically seeing the effects of designer drugs in the emergency room, office examination room, or hospital - drug monitoring using mass spectrometry is a critical tool to identify and prevent the use of designer drugs. Consequently, physicians are increasingly relying on specialty laboratories to help identify the compounds present in patients who are taking controlled medications who are at risk for drug misuse or abuse. Tackling the threat to public health posed by the proliferation of designer drugs will require efforts from multiple stakeholders. Policymakers are beginning to take important action. In addition to the national ban on several types of synthetic drugs signed this summer by President Obama, both New Jersey and Washington, D.C., have enacted similar bans in recent weeks.5,6 But the new laws will not save lives without additional action and support. Regulators and the DEA could make better use of advanced drug detection technologies to more quickly classify new designer drugs as illegal. Insurance companies must be encouraged to support these efforts by ensuring reimbursement for specialty labs, so that doctors have access to the best technology available to detect and identify designer drug compounds. Data about drug use trends must be provided to the DEA and physicians to educate clinicians on any new dangerous drugs - and physicians must be vigilant in testing patients who are at risk for drug abuse and misuse. Finally, the public must be educated about this dangerous category of drugs - especially because users commonly assume that if a drug is not technically "illegal," it is safe to use. In summary, we have a new major public health threat that represents just the latest step in man's creative pursuit of new ways to get high. History tells us that we can't completely eliminate this threat, but by pooling our knowledge and streamlining legal and regulatory processes, we can succeed in reducing the threat of designer drugs and enhancing public safety. It is the collective responsibility of public agencies, specialty labs, physicians, regulators, and health insurers to pool their knowledge and resources to help improve individuals' safety and the safety of the communities they live in. ~~~ 1http://www.drugabuse.gov/about-nida/directors-page/messages-director/2011/02/bath-salts-emerging-dangerous-products 2 FLASHCARD: National Institute of Health, National Institute of Drug Abuse (2012, May). DrugFacts: Spice (Synthetic Marijuana). 3 American Association of Poison Control Centers, Synthetic Drugs Data and Fact Sheets, Bath Salts and Synthetic Marijuana (September 2012). 4 SLIDE DECK: http://www.aapcc.org/dnn/Portals/0/Synthetic%20Marijuana%20Data%20for%20Website%208.2012.pdf 5 Howell T. D.C. joins states on synthetic drug ban. Washington Times. Nov 29, 2012. http://www.washingtontimes.com/news/2012/nov/29/dc-joins-states-on-synthetic-drug-ban-first-appear/#ixzz2DjTy5B3k 6 Queally J. N.J. permanently bans synthetic marijuana. The Star-Ledger. Nov 26, 2012. http://www.nj.com/news/index.ssf/2012/11/nj_permanently_bans_synthetic.html Images: Ameritox Follow Scientific American on Twitter @SciAm and @SciamBlogs. Visit ScientificAmerican.com for the latest in science, health and technology news.
    ? 2013 ScientificAmerican.com. All rights reserved.

    Source: http://news.yahoo.com/seeking-higher-ground-dangers-designer-drugs-121500822.html

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    Tuesday, January 22, 2013

    Al Green: Turned down 'Together' time with Obamas

    FILE - This July 5, 2009 file photo shows Al Green performing during the Essence Music Festival in New Orleans. Jennifer Hudson sang Green's classic "Let's Stay Together," at an inaugural ball Monday, Jan. 21, 2013, leaving many to wonder why the soul legend wasn't singing his own hit for President Barack Obama and first lady Michelle Obama. In a statement to The Associated Press, his representative said Green had been asked to sing, but scheduling conflicts prevented him from attending Monday's festivities. Green said he'd be honored to sing for the president in the future. (AP Photo/Patrick Semansky, file)

    FILE - This July 5, 2009 file photo shows Al Green performing during the Essence Music Festival in New Orleans. Jennifer Hudson sang Green's classic "Let's Stay Together," at an inaugural ball Monday, Jan. 21, 2013, leaving many to wonder why the soul legend wasn't singing his own hit for President Barack Obama and first lady Michelle Obama. In a statement to The Associated Press, his representative said Green had been asked to sing, but scheduling conflicts prevented him from attending Monday's festivities. Green said he'd be honored to sing for the president in the future. (AP Photo/Patrick Semansky, file)

    President Barack Obama bows as he and first lady Michelle Obama, wearing a ruby colored chiffon and velvet Jason Wu gown, gets ready to dance as singer Jennifer Hudson, right, sings Al Green's "Let's Stay Together" at the Inaugural Ball at the Washington Convention Center during the 57th Presidential Inauguration in Washington, Monday, Jan. 21, 2013. (AP Photo/Charles Dharapak)

    Al Green says if things had worked out, it would have been him serenading President Barack Obama and first lady Michelle at the inaugural ball.

    Jennifer Hudson sang Green's classic "Let's Stay Together," leaving many to wonder why the soul legend wasn't singing his own hit for the first couple.

    In a statement to The Associated Press, his representative said Green had been asked to sing, but scheduling conflicts prevented him from attending Monday's festivities. Green said he'd be honored to sing for the president in the future.

    The Presidential Inaugural Committee did not immediately respond to a request for comment.

    Obama famously sang a snippet of the song at an event last year that Green attended.

    ___

    Nekesa Mumbi Moody is the AP's global entertainment and lifestyles editor. Follow her at http://www.twitter.com/nekesamumbi

    Associated Press

    Source: http://hosted2.ap.org/APDEFAULT/4e67281c3f754d0696fbfdee0f3f1469/Article_2013-01-22-Inauguration-Al%20Green/id-62c60733223840169e31eba3757df4dd

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    First video of squid sex reveals deep-sea Kama Sutra

    Sandrine Ceurstemont, editor, New Scientist TV

    Think deep-sea squid have sex in the missionary position? Now the first video capturing a pair in the act is revealing the unexpected details of cephalopod coupling in the abyss.

    The clip, filmed by a National Oceanic and Atmospheric Administration (NOAA) submersible in the Gulf of Mexico last year, allowed Michael Vecchione from the Smithsonian Institution and colleagues to observe for the first time how a male squid uses its penis to transfer packets of sperm. They were surprised at the sexual position the pair adopted: the male was upside down on top of the female and back to front, with his arms around her head. There are a few possible reasons for this arrangement: it could be out of comfort (for the female), or to allow the male to access the best spot for his sperm, but it's also thought to prevent the female from grabbing and perhaps eating her partner.

    As the male holds his partner in what appears to be a firm grip, the video shows the penis extending out to make contact with the female's back. Although a package of sperm is usually deposited during the process, a transfer isn't visible in this clip. Squid caught by trawlers have revealed that the sperm mass is usually somehow implanted deep into the female's tissues, in some species randomly all over her body but in others at the base of the arms. The packet remains in place until her eggs are ready to be fertilised.

    Many squid species use a modified arm, instead of a penis, to deliver sperm. It's very rare to come across a pair of mating squid.

    If you enjoyed this post, watch a male crayfish get turned on by urine or see the first camera trap footage of Asian elephants having sex.

    Subscribe to New Scientist Magazine

    Source: http://feeds.newscientist.com/c/749/f/10897/s/27bcd79f/l/0L0Snewscientist0N0Cblogs0Cnstv0C20A130C0A10Cfirst0Evideo0Eof0Esquid0Esex0Ereveals0Edeep0Esea0Ekama0Esutra0Bhtml0Dcmpid0FRSS0QNSNS0Q20A120EGLOBAL0Qonline0Enews/story01.htm

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    Vegetarian Recipe: Highland Park Lemon Salt | Good Food

    Home ? Featured, Recipes, Veg

    Every week on the Good Food Blog we celebrate Meatless Monday by sharing a vegetarian recipe from our archives.

    Sharon Lovejoy is a gardener and author of books such as Trowel & Error: Over 700 Shortcuts, Tips & Remedies for the Gardener and Roots, Shoots, Buckets & Boots: Gardening Together With Children, published by Workman. ? She first shared this recipe for Highland Park Lemon Salt on January 15, 2005.

    Keep reading for the full recipe?

    ?

    Highland Park Lemon Salt

    • 1 Tablespoon dried zest of Meyer lemon
    • 1 Tablespoon dried lemon verbena leaves (chopped fine)
    • 2 Tablespoons Malden?s sea salt

    Blend all ingredients together and store in an airtight container. Use sparingly on salads, potatoes, rice, and dips.

    ?

    Source: http://blogs.kcrw.com/goodfood/2013/01/vegetarian-recipe-highland-park-lemon-salt/

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    Michelle Obama wears Wu to the balls again

    WASHINGTON (AP) ? Michelle Obama made it a fashion tradition Monday night, wearing a custom-made Jason Wu gown to the inauguration balls. The ruby-colored dress was a follow-up to the white gown Wu made for her four years ago when she was new to Washington, the pomp and circumstance, and the fashion press.

    She now emerged in velvet and chiffon as a bona fide trendsetter.

    "I can't believe it. It's crazy," said Wu, reached at his Manhattan studio. "To have done it once was already the experience of my life. To have a second time is tremendous."

    President Barack Obama also struck a similar style chord to his first-term inaugural balls: He wore a white tie with his tuxedo.

    The red halter dress was the only one Wu, who went from fashion insider to household name on this night in 2009, submitted for Mrs. Obama's consideration. He collaborated with jeweler Kimberly McDonald on the jeweled neckline. "For this occasion, it had to be real diamonds," Wu said.

    He said he felt the dress showed how he has grown up as a designer ? and how Mrs. Obama's style has evolved to be even more confident.

    The first family headed out to inaugural festivities earlier on Monday with Mrs. Obama leading a very coordinated fashion parade in a navy-silk, checkered-patterned coat and dress by Thom Browne that were inspired by a menswear necktie.

    The outfit was specifically designed for Mrs. Obama, but Browne said he wasn't 100 percent sure she was going to wear it until she came out with it on at Inauguration. "I am proud and humbled," he said.

    The rest of Mrs. Obama's Inauguration Day outfit included a belt from J. Crew, necklace by Cathy Waterman and a cardigan by Reed Krakoff, whose ensemble she also wore to yesterday's intimate, indoor swearing-in ceremony.

    Obama wore a blue tie with his white shirt, dark suit and overcoat. Malia Obama had on a plum-colored J. Crew coat with the hemline of an electric-blue dress peeking out and a burgundy-colored scarf, and her younger sister Sasha had on a Kate Spade coat and dress in a similar purple shade.

    "It is an honor that Sasha Obama chose to wear Kate Spade New York," said the company's creative director, Deborah Lloyd, in an email to the Associated Press. "She epitomizes the youthful optimism and colorful spirit of the brand. We are so proud to have been a part of this historic moment."

    Jenna Lyons, creative director of J. Crew, said it was "a huge point of pride for all of us" to be a part of the day ? as the brand was back in 2009 when the girls wore outfits by CrewCuts, its children's label.

    "It's amazing to see the evolution of the family. I love the way Michelle looks. She looks beautiful in something so clean and tailored. It's such an elegant choice," Lyons said, "and they all look so sophisticated! You can see how the girls have grown up in the four years, and they're still so alive and vibrant, but more sophisticated."

    The vice president's wife, Jill Biden, wore a gray coat and dress by American designer Lela Rose.

    Mrs. Obama has worn Browne's designs for other occasions, including a gray dress with black lace overlay to one of the presidential debates last fall, and she honored him last summer at the Smithsonian's Cooper-Hewitt National Design Awards for his contribution to fashion.

    Browne made his name in modern ? very modern ? menswear, but he launched womenswear in 2011. He was in Paris on Monday, just finishing previews for his next menswear collection. The idea to use the tie fabric came to him because he was indeed designing these men's clothes at the same time, he explained.

    "I wanted 'tailored' for her. For me, she stands for strength and confidence, and that's what I wanted to design for her," he said.

    Simon Collins, dean of the school of fashion at Parsons The New School for Design in New York, said the Obamas dressed in their typical fashion: one that shows pride in their appearance.

    "They are a stylish couple and their children look fabulous. Too many people get dressed in the dark," he said. "They show it's good to dress up, take pride in how you look. ... It's a wonderful example for America and the rest of the world."

    He also noted that the Obamas seem to understand that the fashion industry is a driving force in the U.S. economy and that its lobby is a powerful one. They don't treat fashion frivolously, he observed.

    The first lady "is so supportive of so many American designers," Browne noted.

    But Collins said he was a bit surprised the public doesn't pay much attention to the president's wardrobe. He joked that Obama should perhaps try one of Browne's signature shrunken suits ? the ones that show a man's ankles.

    At the end of the Inaugural festivities, Mrs. Obama's outfit and accompanying accessories will go to the National Archives.

    ___

    Samantha Critchell tweets fashion at (at)AP_Fashion, and can be reached on Twitter at (at)Sam_Critchell.

    Source: http://news.yahoo.com/michelle-obama-wears-wu-balls-again-021233810.html

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